Management of bacterial infection in the liver transplant candidate

World J Hepatol. 2018 Feb 27;10(2):222-230. doi: 10.4254/wjh.v10.i2.222.

Abstract

Bacterial infection (BI) is a common cause of impairment of liver function in patients with cirrhosis, especially in the liver transplant candidates. These patients share an immunocompromised state and increased susceptibility to develop community and hospital-acquired infections. The changing epidemiology of BI, with an increase of multidrug resistant strains, especially in healthcare-associated settings, represents a critical issue both in the waiting list and in the post-operative management. This review focused on the role played by BI in patients awaiting liver transplantation, evaluating the risk of drop-out from the waiting list, the possibility to undergo liver transplantation after recovery from infection or during a controlled infection.

Keywords: Bacterial infection; Cirrhosis; Liver transplantation; Portal hypertension.

Publication types

  • Review