L-carnitine and Vitamin B Complex for the Treatment of Pegasparaginase-induced Hyperbilirubinemia

Clin Lymphoma Myeloma Leuk. 2018 May;18(5):e191-e195. doi: 10.1016/j.clml.2018.02.014. Epub 2018 Feb 26.

Authors

Caitlin R Rausch¹, Shilpa Paul¹, Kayleigh R Marx¹, Elias Jabbour², Naveen Pemmaraju², Alessandra Ferrajoli³, Hagop Kantarjian²

Affiliations

¹ Division of Pharmacy, University of Texas MD Anderson Cancer Center, Houston, TX.
² Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX.
³ Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX. Electronic address: [email protected].

PMID: 29550108
DOI: 10.1016/j.clml.2018.02.014

No abstract available

Keywords: Acute lymphoblastic leukemia; Allogeneic stem cell transplantation; Asparaginase; Hepatotoxicity; Levocarnitine.

Publication types

Case Reports

MeSH terms

Adult
Antineoplastic Agents / adverse effects*
Asparaginase / adverse effects*
Bilirubin / blood
Carnitine / administration & dosage*
Female
Humans
Hyperbilirubinemia / chemically induced*
Hyperbilirubinemia / drug therapy*
Male
Polyethylene Glycols / adverse effects*
Treatment Outcome
Vitamin B Complex / administration & dosage*
Young Adult

Substances

Antineoplastic Agents
Vitamin B Complex
Polyethylene Glycols
pegaspargase
Asparaginase
Bilirubin
Carnitine