Fascin is secreted in male's serum: results of a pilot study

Daniel Porav-Hodade; Orsolya Martha; Daniel Balan; Sabin Tataru; Adina Hutanu; Anca Sin; Mihai Dorin Vartolomei

doi:10.4155/fsoa-2017-0098

Fascin is secreted in male's serum: results of a pilot study

Future Sci OA. 2018 Jan 5;4(3):FSO273. doi: 10.4155/fsoa-2017-0098. eCollection 2018 Mar.

Authors

Daniel Porav-Hodade^{1

1}, Orsolya Martha^{1

1}, Daniel Balan^{2

2}, Sabin Tataru^{1

1}, Adina Hutanu^{3

3}, Anca Sin^{2

2}, Mihai Dorin Vartolomei^{2

4

2

4}

Affiliations

¹ University of Medicine & Pharmacy Tirgu Mures, Department of Urology, Tirgu Mures, Romania.
² University of Medicine & Pharmacy Tirgu Mures, Department of Cell & Molecular Biology, Tirgu Mures, Romania.
³ University of Medicine & Pharmacy Tirgu Mures, Department of Laboratory Medicine, Tirgu Mures, Romania.
⁴ Medical University Vienna, Department of Urology, Vienna, Austria.

Abstract

Aim: Fascin is a 55 kDa globular protein with an important role in cell migration. Aim of study was to investigate serum fascin in healthy males.

Materials & methods: From 1 July 2016 to 31 December 2016, we collected serum from 46 males. Serum fascin level was performed using ELISA kit from USBiological (Salem, MA, USA).

Results: Median age was 64 years. Mean fascin serum level was 9.84 ng/ml, mean prostate-specific antigen (PSA) was 2.74 ng/ml and mean prostate volume was 37.64 cc. The 51-60 years group had a mean of 10.53 ng/ml, the 61-70 group a mean of 9.7 ng/ml and the 71-80 group had a mean of 9.41 ng/ml fascin serum level.

Conclusion: Fascin serum level did not differ according to age in males.

Keywords: biomarker; fascin; serum.