Isolated cutaneous mucormycosis in a pediatric renal transplant recipient

Mallory L Downie; Mohammad Alghounaim; Kristen M Davidge; Yvonne Yau; Thomas J Walsh; Elena Pope; Gino R Somers; Valerie Waters; Lisa A Robinson

doi:10.1111/petr.13172

Isolated cutaneous mucormycosis in a pediatric renal transplant recipient

Pediatr Transplant. 2018 Jun;22(4):e13172. doi: 10.1111/petr.13172. Epub 2018 Mar 23.

Authors

Mallory L Downie¹, Mohammad Alghounaim², Kristen M Davidge³, Yvonne Yau⁴, Thomas J Walsh⁵, Elena Pope⁶, Gino R Somers⁷, Valerie Waters⁸, Lisa A Robinson¹

Affiliations

¹ Division of Nephrology, Department of Paediatrics, The Hospital for Sick Children, Toronto, ON, Canada.
² Division of Infectious Diseases, Departments of Pediatrics & Medical Microbiology, The Montreal Children's Hospital, McGill University Health Centre, Montreal, QC, Canada.
³ Division of Plastic & Reconstructive Surgery, Department of Surgery, The Hospital for Sick Children, Toronto, ON, Canada.
⁴ Division of Microbiology, Department of Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada.
⁵ Transplantation-Oncology Infectious Diseases Program, Weill Cornell University Medical Center, New York, NY, USA.
⁶ Section of Dermatology, Department of Paediatrics, The Hospital for Sick Children, Toronto, ON, Canada.
⁷ Division of Pathology, The Hospital for Sick Children, Toronto, ON, Canada.
⁸ Division of Infectious Diseases, Department of Paediatrics, The Hospital for Sick Children, Toronto, ON, Canada.

PMID: 29569805
DOI: 10.1111/petr.13172

Abstract

Mucormycosis is a rare and potentially life-threatening infection, typically affecting immunocompromised hosts. We report a case of an adolescent boy who developed primary isolated cutaneous mucormycosis in the early period following kidney transplantation. Surgical excision was performed using intraoperative fungal staining to obtain clear margins, followed by topical and systemic antifungal therapy. A skin graft was then applied to the excised area with good healing, and the patient made a full recovery.

Keywords: Rhizopus; fungal; mucormycosis; pediatric; transplant.

Publication types

Case Reports

MeSH terms

Adolescent
Dermatomycoses / diagnosis*
Dermatomycoses / etiology
Humans
Kidney Transplantation*
Male
Mucormycosis / diagnosis*
Mucormycosis / etiology
Postoperative Complications / diagnosis*