Development of a congenital cardiovascular computed tomography imaging registry: Rationale and implementation

J Cardiovasc Comput Tomogr. 2018 May-Jun;12(3):263-266. doi: 10.1016/j.jcct.2018.03.006. Epub 2018 Mar 16.

Abstract

Background: The cumulative exposure and risk of anesthesia, vascular access, contrast agents and radiation is emerging as a significant lifelong burden in patients with congenital heart disease (CHD). Latest generation computerized tomographic (CT) scanners are increasingly used for high resolution cardiovascular imaging and have both hardware and post processing radiation dose reduction strategies that can be implemented. Currently, these dose reduction strategies are not uniformly applied and there is a large variability in radiation dose used for the performance of CT in CHD.

Methods: We propose the development and implementation of a prospective, multi-center and multi-specialty consortium to measure the variability of use, risk and image quality of CT scans in patients of all ages with CHD. The primary goals of this collaboration are 1) define variability of use, diagnostic quality, and risk of cardiac CT 2) establish best practice guidelines designed to optimize diagnostic image quality with appropriate use of radiation and anesthesia exposure 3) provide institution specific feedback compared with the group norm across participating centers 4) improve the level of evidence for the use of CT in CHD through the collection of prospective and multi-institutional data.

Conclusions: Prospective multi-institutional data is needed to inform risk estimates of CT in CHD using current generation scanners and aggressive dose optimization techniques. This registry will provide a platform for future collaboration establishing a multi-modality risk assessment tool specific to patients with CHD.

Keywords: Cardiac catheterization; Cardiomyopathy; Computerized tomographic; Congenital heart disease; Image quality; Magnetic resonance imaging; Risk.

Publication types

  • Multicenter Study
  • Observational Study

MeSH terms

  • Databases, Factual
  • Europe
  • Heart Defects, Congenital / diagnostic imaging*
  • Heart Defects, Congenital / therapy
  • Humans
  • North America
  • Observer Variation
  • Predictive Value of Tests
  • Prognosis
  • Prospective Studies
  • Radiation Dosage
  • Radiation Exposure
  • Registries*
  • Reproducibility of Results
  • Research Design
  • Risk Assessment
  • Risk Factors
  • Tomography, X-Ray Computed* / adverse effects
  • Tomography, X-Ray Computed* / standards