The Microvasculature and Skeletal Muscle Health in Aging

Rian Q Landers-Ramos; Steven J Prior

doi:10.1249/JES.0000000000000151

The Microvasculature and Skeletal Muscle Health in Aging

Exerc Sport Sci Rev. 2018 Jul;46(3):172-179. doi: 10.1249/JES.0000000000000151.

Authors

Rian Q Landers-Ramos^{1

2}, Steven J Prior^{1

2

3}

Affiliations

¹ Baltimore Veterans Affairs Geriatric Research, Education and Clinical Center.
² Department of Medicine, University of Maryland School of Medicine, Baltimore.
³ Department of Kinesiology, University of Maryland School of Public Health, College Park, MD.

Abstract

Aging and aging-related declines in physical activity are associated with physical and metabolic impairments. Skeletal muscle capillarization is reduced in sedentary older adults, may contribute to impairments in skeletal muscle, and is modifiable by exercise training. This article examines the hypothesis that preservation of skeletal muscle capillarization is essential to maintain metabolism, fitness, and function with aging.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Review

MeSH terms

Aging / physiology*
Animals
Cardiorespiratory Fitness
Exercise / physiology*
Glucose / metabolism
Humans
Microvessels / physiology*
Muscle, Skeletal / blood supply*
Muscle, Skeletal / physiology

Substances

Glucose

Abstract

Publication types

MeSH terms

Substances

Grants and funding