Breast lymphoma occurring after an invasive ductal breast carcinoma developed in the same area: A case report and literature review

Cancer Radiother. 2018 Apr;22(2):167-170. doi: 10.1016/j.canrad.2017.11.005. Epub 2018 Apr 12.

Abstract

Chemo- and radiotherapy are treatments very helpful to cure cancers but are also well known for adverse effects such as secondary cancers. Breast cancers following Hodgkin lymphoma have been relatively well studied. Breast cancers after radiotherapy covering or nearby breasts or nipples are usually carcinomas or secondary sarcomas. Among the big cohort of patients treated for breast carcinomas, breast lymphomas developed in the same area are not usual. Nevertheless, published studies described a significant increased risk of non-Hodgkin lymphoma after initial radiotherapy for a solid cancer. Here, we report a case of a secondary breast lymphoma observed in a 53-year-old woman treated 13 years before for a ductal carcinoma and analyse such second tumors with a review of the literature. This case report emphasizes the importance of the biopsy in case of recurrence in breast cancer to give the appropriate treatment.

Keywords: Biopsie; Biopsy; Breast cancer; Breast lymphoma; Cancer du sein; Cancers secondaires; Lymphome mammaire; Lymphome non hodgkinien; Non Hodgkin lymphoma; Secondary cancers.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Breast Neoplasms / diagnostic imaging
  • Breast Neoplasms / pathology*
  • Carcinoma, Ductal, Breast / pathology
  • Female
  • Humans
  • Lymphoma, Large B-Cell, Diffuse / diagnostic imaging
  • Lymphoma, Large B-Cell, Diffuse / pathology*
  • Lymphoma, Large B-Cell, Diffuse / therapy
  • Magnetic Resonance Imaging
  • Mastectomy, Segmental
  • Middle Aged
  • Neoplasms, Second Primary / diagnostic imaging
  • Neoplasms, Second Primary / pathology*
  • Neoplasms, Second Primary / therapy
  • Positron-Emission Tomography