The women's heart health programme: a pilot trial of sex-specific cardiovascular management

BMC Womens Health. 2018 Apr 16;18(1):56. doi: 10.1186/s12905-018-0548-6.

Abstract

Background: There is increasing knowledge of sex-specific differences in cardiovascular disease and recognition of sex disparities in management. In our study, we investigated whether a cardiovascular programme tailored to the specific needs of women could lead to improved outcomes.

Methods: We randomised 100 female patients to receive cardiology follow-up with the conventional sex-neutral cardiac programme (control), or the sex-tailored Women's Heart Health Programme (intervention). The intervention group was managed by an all-women multidisciplinary team and received culture-centred health intervention workshops, designed through in-depth interviews with the participants. The primary outcome was cardiovascular risk factor improvement at 1 year. Secondary outcomes include cardiovascular event rates, quality of life scores, and self-reported improvement in knowledge, attitudes, intentions and practices. Generalised structural equation model analysis was used to determine if the intervention group had better outcomes at alpha level 0.1.

Results: The mean age was 67.3 ± 12.7 years, with an ethnic distribution of 70% Chinese, 18% Malays, and 12% Indians. The majority of these patients had no formal or primary level of education (63%), and were mostly unemployed (78%). Patients in intervention group had better control of diabetes mellitus (lower HbA1c of 0.63% [CI 0.21-1.04], p = 0.015) and lower body-mass-index (0.74 kg/m2 [CI 0.02-1.46], p = 0.092) at 1 year, but there was no significant difference in blood pressure or lipid control. Overall, there was a trend towards better risk factor control, 31.6% of intervention group versus 26.5% of control group achieved improvement in at least 1 CV risk factor control to target range. There was no significant difference in incidence of cardiovascular events, quality of life, or domains in knowledge, attitudes, intention and practices.

Conclusion: This pilot study is the first of its kind evaluating a new model of care for women with heart disease. The potential to improve outcomes needs to be studied in a larger trial with longer follow up.

Trial registration: This trial was prospectively registered clinicaltrials.gov on 6 May 2013. Trial Number: 2013/00088. Identifier: NCT02017470.

Keywords: Attitudes; Cardiovascular disease; Culturally competent care; Health knowledge; Healthcare disparities; Practice; Quality of life; Women’s health.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Blood Pressure
  • Body Mass Index
  • Cardiovascular Diseases / prevention & control*
  • Diabetes Mellitus / blood
  • Female
  • Glycated Hemoglobin / metabolism
  • Health Knowledge, Attitudes, Practice*
  • Health Promotion*
  • Humans
  • Lipoproteins, HDL / blood
  • Lipoproteins, LDL / blood
  • Middle Aged
  • Patient Education as Topic*
  • Pilot Projects
  • Quality of Life
  • Risk Factors
  • Sex Factors
  • Women's Health

Substances

  • Glycated Hemoglobin A
  • Lipoproteins, HDL
  • Lipoproteins, LDL
  • hemoglobin A1c protein, human

Associated data

  • ClinicalTrials.gov/NCT02017470