Deficiency of the interleukin-36 receptor antagonist dramatically improved by secukinumab

J Dermatol. 2018 Oct;45(10):e280-e281. doi: 10.1111/1346-8138.14330. Epub 2018 Apr 17.

Authors

Manao Kinoshita¹, Takashi Okamoto¹, Shinya Sano¹, Hiroshi Mitsui¹, Takuya Takeichi², Kazumitsu Sugiura³, Masashi Akiyama², Shinji Shimada¹, Tatsuyoshi Kawamura¹

Affiliations

¹ Department of Dermatology, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan.
² Department of Dermatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
³ Department of Dermatology, Fujita Health University School of Medicine, Toyoake, Japan.

PMID: 29665114
DOI: 10.1111/1346-8138.14330

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Adult
Antibodies, Monoclonal / therapeutic use*
Antibodies, Monoclonal, Humanized
DNA Mutational Analysis
Humans
Interleukins / deficiency*
Interleukins / genetics
Male
Mutation
Psoriasis / diagnosis
Psoriasis / drug therapy*
Psoriasis / genetics
Psoriasis / pathology
Severity of Illness Index
Skin / pathology
Torso
Treatment Outcome

Substances

Antibodies, Monoclonal
Antibodies, Monoclonal, Humanized
IL36RN protein, human
Interleukins
secukinumab