High-resolution 3 T magnetic resonance findings in cochlear hypoplasias and incomplete partition anomalies: a pictorial essay

Br J Radiol. 2018 Sep;91(1089):20180120. doi: 10.1259/bjr.20180120. Epub 2018 May 17.

Abstract

Inner ear malformations are recognized by imaging in about 20% of children with congenital sensorineural hearing loss. Normal development of the inner ear structures can be affected by many factors, including genetic anomalies as well as environmental destructive causes (ischemic, infectious, radiation and more). Recently, histopathological studies have provided new insights on the anatomy and pathogenesis of inner ear malformations, especially regarding incomplete partition and cochlear hypoplasia (CH), for which different subtypes have been identified. Factors known for interfering with normal inner ear development are numerous and sometimes act simultaneously, making the understanding of their pathophysiology more challenging. Vascular supply from the internal auditory canal seems to be critical for normal development of internal structures of the labyrinth while a premature arrest in the spatial development of the cochlea due to genetic or toxic factors may result in short cochlea (i.e.: CH). The aim of this essay is to show 3 T MRI appearances of the different subtypes of CH and incomplete partition introduced in the new classification (findings summary in Table 1).

Publication types

  • Review

MeSH terms

  • Child, Preschool
  • Cochlea / abnormalities*
  • Cochlea / diagnostic imaging*
  • Cochlea / pathology
  • Female
  • Humans
  • Infant
  • Magnetic Resonance Imaging / methods*
  • Male