A Future for Autologous Hematopoietic Stem Cell Transplantation in Type 1 Diabetes

Kayleigh M van Megen; Ernst-Jan T van 't Wout; Stephen J Forman; Bart O Roep

doi:10.3389/fimmu.2018.00690

A Future for Autologous Hematopoietic Stem Cell Transplantation in Type 1 Diabetes

Front Immunol. 2018 Apr 6:9:690. doi: 10.3389/fimmu.2018.00690. eCollection 2018.

Authors

Kayleigh M van Megen¹, Ernst-Jan T van 't Wout¹, Stephen J Forman², Bart O Roep^{1

3}

Affiliations

¹ Department of Diabetes Immunology, Diabetes & Metabolism Research Institute, Beckman Research Institute at the City of Hope, Duarte, CA, United States.
² Department of Hematology & Hematopoietic Cell Transplantation, T Cell Therapeutics Research Laboratory, City of Hope Beckman Research Institute and Medical Center, Duarte, CA, United States.
³ Department of Immunohaematology and Blood Transfusion, Leiden University Medical Center, Leiden, Netherlands.

No abstract available

Keywords: autologous hematopoietic stem cell transplantation; beta cells; immune regulation; immunotherapy; insulin independence; personalized therapy; type 1 diabetes.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Diabetes Complications
Diabetes Mellitus, Type 1 / therapy*
Hematopoietic Stem Cell Transplantation*
Humans
Insulin-Secreting Cells / immunology
Transplantation, Autologous