Prevalence of Nephrocalcinosis in Pseudohypoparathyroidism: Is Screening Necessary?

David W Hansen; Todd D Nebesio; Linda A DiMeglio; Erica A Eugster; Erik A Imel

doi:10.1016/j.jpeds.2018.03.003

Prevalence of Nephrocalcinosis in Pseudohypoparathyroidism: Is Screening Necessary?

J Pediatr. 2018 Aug:199:263-266. doi: 10.1016/j.jpeds.2018.03.003. Epub 2018 Apr 23.

Authors

David W Hansen¹, Todd D Nebesio², Linda A DiMeglio², Erica A Eugster², Erik A Imel³

Affiliations

¹ Section of Pediatric Endocrinology and Diabetology, Riley Hospital for Children, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN. Electronic address: [email protected].
² Section of Pediatric Endocrinology and Diabetology, Riley Hospital for Children, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN.
³ Section of Pediatric Endocrinology and Diabetology, Riley Hospital for Children, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN; Division of Endocrinology & Metabolism, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN.

Abstract

The prevalence of nephrocalcinosis in persons with pseudohypoparathyroidism has not been systematically examined. We conducted a retrospective study of renal imaging and biochemical results in 19 patients with pseudohypoparathyroidism with 49 imaging assessments. No cases of nephrocalcinosis were identified. Routine screening for nephrocalcinosis in pseudohypoparathyroidism may not be necessary.

Keywords: PTH, phosphate; calcium; parathyroid hormone; pseudohypoparathyroidism.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Adolescent
Child
Child, Preschool
Female
Humans
Infant
Male
Mass Screening
Nephrocalcinosis / diagnosis*
Nephrocalcinosis / epidemiology
Nephrocalcinosis / etiology*
Prevalence
Pseudohypoparathyroidism / complications*
Retrospective Studies
Risk Factors

Abstract

Publication types

MeSH terms

Grants and funding