A chance to cut (the genome) is a chance to cure

Blood. 2018 Apr 26;131(17):1884-1885. doi: 10.1182/blood-2018-03-839787.

Abstract

In this issue of Blood, Antoniani et al identify an innovative genome editing approach to induce fetal hemoglobin (HbF), which may eventually lead to therapeutic strategies for ameliorating or curing sickle-cell disease (SCD) and β-thalassemia.

Publication types

  • Comment

MeSH terms

  • CRISPR-Cas Systems
  • Clustered Regularly Interspaced Short Palindromic Repeats
  • Female
  • Fetal Hemoglobin*
  • Humans
  • Pregnancy
  • Prenatal Care
  • beta-Globins*

Substances

  • beta-Globins
  • Fetal Hemoglobin