The salience network and human personality: Integrity of white matter tracts within anterior and posterior salience network relates to the self-directedness character trait

Brain Res. 2018 Aug 1:1692:66-73. doi: 10.1016/j.brainres.2018.04.035. Epub 2018 Apr 30.

Abstract

A prevailing topic in personality neuroscience is the question how personality traits are reflected in the brain. Functional and structural networks have been examined by functional and structural magnetic resonance imaging, however, the structural correlates of functionally defined networks have not been investigated in a personality context. By using the Temperament and Character Inventory (TCI) and Diffusion Tensor Imaging (DTI), the present study assesses in a sample of 116 healthy participants how personality traits proposed in the framework of the biopsychosocial theory of personality relate to white matter pathways delineated by functional network imaging. We show that the character trait self-directedness relates to the overall microstructural integrity of white matter tracts constituting the salience network as indicated by DTI-derived measures. Self-directedness has been proposed as the executive control component of personality and describes the tendency to stay focused on the attainment of long-term goals. The present finding corroborates the view of the salience network as an executive control network that serves maintenance of rules and task-sets to guide ongoing behavior.

Keywords: Character; Personality neuroscience; Resting-state networks; Salience network; Structural connectivity; Temperament.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Analysis of Variance
  • Diffusion Tensor Imaging
  • Executive Function / physiology
  • Female
  • Humans
  • Image Processing, Computer-Assisted
  • Male
  • Nerve Fibers, Myelinated
  • Neural Pathways / diagnostic imaging*
  • Personality*
  • Self Concept*
  • Surveys and Questionnaires
  • White Matter / diagnostic imaging*
  • Young Adult