Skeletal muscle amino acid transporter and BCAT2 expression prior to and following interval running or resistance exercise in mode-specific trained males

Amino Acids. 2018 Jul;50(7):961-965. doi: 10.1007/s00726-018-2570-2. Epub 2018 May 3.

Abstract

Endurance (END)- and resistance (RES)-trained males performed interval running or resistance exercise during three consecutive days (bouts 1-3). Muscle biopsies were obtained at baseline, 2 h post-bout 1, and 72 h post-bout 3. Amino acid transporter SNAT2 mRNA was 75% greater in END (group p = 0.008), and increased ~ 70% 2 h post in both groups (time p = 0.023). Amino acid transporter PAT1 mRNA was 2.7-fold greater in RES (group p = 0.002). Baseline protein levels of the mitochondrial aminotransferase BCAT2 were 79% greater in END (p = 0.015).

Keywords: BCAT2; Endurance exercise; PAT1; Resistance exercise; SNAT2.

MeSH terms

  • Adult
  • Humans
  • Male
  • Minor Histocompatibility Antigens / biosynthesis*
  • Muscle, Skeletal / metabolism*
  • Physical Endurance / physiology*
  • Pregnancy Proteins / biosynthesis*
  • Resistance Training*
  • Running / physiology*
  • Time Factors
  • Transaminases / biosynthesis*

Substances

  • Minor Histocompatibility Antigens
  • Pregnancy Proteins
  • Transaminases
  • BCAT2 protein, human