At present, the study of erectile dysfunction depends heavily on animal models, but the differences in anatomy and physiology of currently used animals make it difficult to exceed the limitations on the experiment. In order to make the results of experiments more applicable and beneficial to the public, it is essential to establish most suitable animal models for the study of the sexual function of humans. Moreover, a consensus has not yet been reached on the methods of detecting and evaluating the erectile function of animals, and therefore an informative and instructional summary of the existing methods seems even more necessary. This article discusses how to establish and evaluate the animal models of different types of erectile dysfunction.
目前对于勃起功能障碍(ED)的研究极大地依赖于动物模型,但常用实验动物的在解剖、生理上的差异决定了其在进行勃起功能实验上的局限性,为了使实验成果更加合理有效并惠及人类,选用合适的动物模型对于男性性功能研究十分必要。此外,目前动物勃起功能的检测方法及评价指标尚未达成一致,因此归纳探讨现有方法对筛选动物模型有一定的指导意义。本文就不同类型的ED动物模型如何建立及检测评价作一综述。.