1 Department of Surgical and Perioperative Sciences, Umeå University, Sweden, Department of Surgery, Sunderby Hospital, Sweden, Sunderby Hosptial, SWEDEN, Luleå Department of Surgical and Perioperative Sciences, Umeå University Department of Surgical and Perioperative Sciences, Umeå University, Departement of Surgery, Sunderby Hospital Departement of Imaging and Physiology, Karolinska University Hospital Department of Surgical and Perioperative Sciences, Umeå University Department of Surgical and Perioperative Sciences, Umeå University, Sunderby Research Unit.