The Role of Lipid Nanoparticles and its Surface Modification in Reaching the Brain: An Approach for Neurodegenerative Diseases Treatment

Curr Drug Deliv. 2018;15(9):1218-1220. doi: 10.2174/1567201815666180510103747.

Authors

Sara Hernando¹, Jose Luis Pedraz^{1

2}, Manoli Igartua^{1

2}, Rosa Maria Hernandez^{1

2}

Affiliations

¹ NanoBioCel Group, Laboratory of Pharmaceutics, School of Pharmacy, University of the Basque Country (UPV/EHU), Vitoria-Gasteiz, 01006, Spain.
² Biomedical Research Networking Centre in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Vitoria-Gasteiz, 01006, Spain.

PMID: 29745334
DOI: 10.2174/1567201815666180510103747

No abstract available

Publication types

Review

MeSH terms

Administration, Intravenous
Biological Availability
Blood-Brain Barrier / drug effects*
Blood-Brain Barrier / metabolism
Central Nervous System Agents / administration & dosage
Central Nervous System Agents / pharmacokinetics*
Cerebrospinal Fluid / metabolism
Drug Carriers / chemistry
Drug Carriers / pharmacology*
Humans
Lipids / chemistry
Lipids / pharmacology*
Nanoparticles / chemistry
Neurodegenerative Diseases / drug therapy*
Surface Properties

Substances

Central Nervous System Agents
Drug Carriers
Lipids