Rapid complete response to blinatumomab as a successful bridge to allogeneic stem cell transplantation in a case of refractory Richter syndrome

Leuk Lymphoma. 2019 Jan;60(1):230-233. doi: 10.1080/10428194.2018.1461862. Epub 2018 May 10.

Authors

Juan Pablo Alderuccio¹, Nicholas Mackrides², Jennifer R Chapman², Francisco Vega², Izidore S Lossos^{1

3}

Affiliations

¹ a Department of Medicine, Division of Hematology , Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine , Miami , FL , USA.
² b Department of Pathology and Laboratory Medicine, Division of Hematopathology , Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine , Miami , FL , USA.
³ c Department of Molecular and Cellular Pharmacology , Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine , Miami , FL , USA.

PMID: 29745744
DOI: 10.1080/10428194.2018.1461862

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Antibodies, Bispecific / therapeutic use*
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
Cell Transformation, Neoplastic / pathology
Disease Progression
Humans
Leukemia, Lymphocytic, Chronic, B-Cell / diagnostic imaging
Leukemia, Lymphocytic, Chronic, B-Cell / pathology
Leukemia, Lymphocytic, Chronic, B-Cell / therapy*
Lymphoma, Large B-Cell, Diffuse / diagnostic imaging
Lymphoma, Large B-Cell, Diffuse / pathology
Lymphoma, Large B-Cell, Diffuse / therapy*
Male
Middle Aged
Neoadjuvant Therapy / methods
Neoplasm Recurrence, Local
Positron Emission Tomography Computed Tomography
Remission Induction / methods
Stem Cell Transplantation*
Transplantation, Homologous
Treatment Outcome

Substances

Antibodies, Bispecific
blinatumomab