Idiopathic Lead Migration: Concept and Variants of an Uncommon Cause of Cardiac Implantable Electronic Device Dysfunction

JACC Clin Electrophysiol. 2017 Nov;3(11):1321-1329. doi: 10.1016/j.jacep.2017.02.015. Epub 2017 May 31.

Abstract

Objectives: This cumulative case study was performed to properly address the possible mechanisms, forms, and consequences of "twiddler's," "reel," and "ratchet" syndromes.

Background: Twiddler's, reel, and ratchet syndromes are rare entities responsible for lead displacement of cardiac implantable electronic devices (CIED).

Methods: From 2007 to 2012, 1,472 CIED were implanted at our center. Eighty-nine cases were reviewed for failure of pacing circuit integrity. Only 9 met the inclusion criteria for idiopathic lead migration (ILM) and were grouped as ILM (twiddler) or ILM (reel). For a pooled analysis of cases, a review of the literature from 1990 to 2012 was performed, and the authors identified 78 cases from 64 publications.

Results: The study population consisted of 87 cases (45 women; median age, 66 years; 46 with ILM [twiddler] and 41 with ILM [reel]). Migration affected only 1 lead in 65% of 46 devices with more than 1 lead. None of the previously reported risk factors-manual manipulation of the device, elderly age, obesity, oversized pocket, and psychiatric history-correlated with the risk of ILM.

Conclusions: Neither manual manipulation of the device nor the other traditional risk factors reported in the literature for ILM syndrome correlated with the risk of ILM.

Keywords: cardiac pacemaker; lead dislodgment; ratchet syndrome; reel syndrome; twiddler’s syndrome.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Child, Preschool
  • Defibrillators, Implantable / adverse effects
  • Electrodes, Implanted / adverse effects*
  • Equipment Design
  • Equipment Failure / statistics & numerical data*
  • Female
  • Foreign-Body Migration / etiology*
  • Humans
  • Male
  • Middle Aged
  • Pacemaker, Artificial / adverse effects*
  • Pacemaker, Artificial / statistics & numerical data
  • Risk Factors
  • Syndrome
  • Young Adult