IgG4-Related Disease Simulating Carcinoma Colon With Diffuse Peritoneal Carcinomatosis on 18F-FDG PET/CT

Clin Nucl Med. 2018 Jul;43(7):e247-e249. doi: 10.1097/RLU.0000000000002140.

Abstract

IgG4-related disease (IgG4-RD) continues to be a diagnostic challenge and a great mimicker of malignancies. We report here a case of young man who presented with subacute intestinal obstruction with initial imaging and clinical features suggestive of carcinoma colon. F-FDG PET/CT showed diffuse peritoneal carcinomatosis pattern typically seen with abdominal malignancies. However, the histopathology and the raised IgG4 levels diagnosed it to be IgG4-RD. Although F-FDG PET/CT has typical patterns corresponding to the multisystemic involvement of IgG4-RD, the index case did not show any such findings.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Autoimmune Diseases / diagnostic imaging*
  • Carcinoma / diagnostic imaging*
  • Colonic Neoplasms / diagnostic imaging*
  • Diagnosis, Differential
  • Fluorodeoxyglucose F18
  • Humans
  • Immunoglobulin G / immunology*
  • Male
  • Peritoneal Neoplasms / diagnostic imaging*
  • Positron Emission Tomography Computed Tomography*
  • Radiopharmaceuticals

Substances

  • Immunoglobulin G
  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18