Usefulness of Simultaneous Screening for HIV- and Hepatitis C-Specific Antibodies and Hepatitis B Surface Antigen by Capillary-Based Multiplex Immunochromatographic Rapid Test to Strengthen Prevention Strategies and Linkage to Care in Childbearing-Aged Women Living in Resource-Limited Settings

Ralph-Sydney Mboumba Bouassa; Zita Aleyo Nodjikouambaye; Damtheou Sadjoli; Ali Mahamat Moussa; Chatte Adawaye; Donato Koyalta; Laurent Bélec

doi:10.1093/ofid/ofy069

Usefulness of Simultaneous Screening for HIV- and Hepatitis C-Specific Antibodies and Hepatitis B Surface Antigen by Capillary-Based Multiplex Immunochromatographic Rapid Test to Strengthen Prevention Strategies and Linkage to Care in Childbearing-Aged Women Living in Resource-Limited Settings

Open Forum Infect Dis. 2018 May 5;5(5):ofy069. doi: 10.1093/ofid/ofy069. eCollection 2018 May.

Authors

Ralph-Sydney Mboumba Bouassa^{1

2}, Zita Aleyo Nodjikouambaye^{1

3}, Damtheou Sadjoli³, Ali Mahamat Moussa^{4

5}, Chatte Adawaye⁶, Donato Koyalta⁷, Laurent Bélec²

Affiliations

¹ Ecole Doctorale Régionale d'Infectiologie Tropicale, Franceville, Gabon.
² Laboratoire de Virologie, Hôpital Européen Georges Pompidou, and Faculté de Médecine Paris Descartes, Université Paris Descartes (Paris V), Sorbonne Paris Cité, Paris, France.
³ Service de Gynécologie-Obstétrique, Hôpital de la Mère et de l'Enfant, and Cabinet Médical de Gynécologie Obstétrique "La Renaissance Plus," N'Djamena, Chad.
⁴ Faculté de Médecine, N'Djamena, Chad.
⁵ Service de Gastro-entérologie, Hôpital Général de Référence Nationale, N'Djamena, Chad.
⁶ Institut National Supérieur des Sciences et Techniques d'Abéché, Abéché, Chad.
⁷ UNAIDS, N'Djamena, Chad.

Abstract

Childbearing-aged women (n = 266) attending a gynecological clinic in Chad were subjected to multiplex immunochromatographic rapid test for HIV, hepatitis B virus (HBV), and hepatitis C virus (HCV). Ten (3.7%) and 8 (3.0%) were seropositive for HIV and HCV, respectively, and 20 (7.5%) for HBV surface antigen, allowing diagnosis of chronic viral infections in 1 of 7 (14.3%) women.

Keywords: Chad; HCV; HIV; childbearing-aged women; hepatitis B surface antigen; multiplex rapid diagnostic test; sub-Saharan Africa.