Objective: To review the research background, biomechanical characteristics, and clinical application of fenestrated pedicle screw (FPS).
Methods: The recent literature about the study and application of FPS was reviewed, analyzed, and summarized.
Results: Compared with the technique of conventional pedicle screw augmentation, FPS can be augmented with polymethyl methacrylate (PMMA) through inner central pore and side holes. Hence, the augmentation process of FPS is more convenient during operation. The biomechanics of PMMA augmented FPS is strong enough for instrumentation in osteoporotic vertebra body and the way of FPS PMMA augmentation can reduce the risk of PMMA leakage.
Conclusions: FPS is an innovation in the technology of spinal instrumentation, which is expected to improve the clinical outcome of PMMA augmented pedicle screw in osteoporotic vertebra body fixation.
目的: 对空心侧孔椎弓根螺钉（fenestrated pedicle screw，FPS）的研发背景、生物力学特征及临床应用进行综述。.
方法: 查阅近年国内外有关FPS的文献并进行综述。.
结果: 与传统椎弓根螺钉钉道强化相比，FPS能够通过中空孔及侧边孔实现聚甲基丙烯酸甲酯（polymethyl methacrylate，PMMA）强化，术中操作更简便。强化后的FPS能够在骨质疏松椎体牢固锚定，同时能降低PMMA渗漏风险。.
结论: FPS是脊柱内固定技术的一大创新，有望提高PMMA强化椎弓根螺钉固定骨质疏松椎体的疗效。.
Keywords: Fenestrated pedicle screw; Osteoporosis; Polymethyl methacrylate.