[Clinical observation of Weisu granules in treating laryngopharyngeal reflux]

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Mar;32(5):369-371. doi: 10.13201/j.issn.1001-1781.2018.05.012.
[Article in Chinese]

Abstract

Objective:To observe the clinical effect of Weisu granules in treating laryngopharyngeal reflux.Method:One hundred and eighty patients were divided into three groups in random. Sixty patients in experimental group combined of Lanqin oral solution and Weisu granules. Sixty patients in control group A using Lanqin oral solution. Sixty patients in control group B using Esomeprazole Magnesium Entericcoated Tablets and Lanqin oral solution. The treatment course ranges from 4 weeks.Result:Four weeks after treatment,clinical symptoms of all the three groups improved significantly. The effective curative rate in experimental group was 91.7% which better than that of the control group A 73.3%(P<0.05). After treatment, the symptoms and signs of the experimental group were significantly different from those in the control group A(P<0.05). There were no significant difference in the experimental group and the control group B(P>0.05).Conclusion:The therapeutic method of Weisu granules using in laryngopharyngeal reflux has obvious effects.

Keywords: Weisu granules; laryngopharyngeal, reflux.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Esomeprazole / therapeutic use*
  • Gastroesophageal Reflux
  • Humans
  • Laryngopharyngeal Reflux / drug therapy*
  • Proton Pump Inhibitors / therapeutic use*

Substances

  • Proton Pump Inhibitors
  • Esomeprazole