Abstract
Two patients developed non-Hodgkin's lymphoma (NHL) six and ten years after radiotherapy and chemotherapy for Hodgkin's disease nodular sclerosis type. The histological classification of the developing NHL for the two patients was: IgG (K) secreting lymphoplasmacytoid lymphoma of the stomach, and immunoblastic lymphoma of the cervical lymph nodes. Both patients responded well to conventional chemotherapy for NHL and are alive 22 and 5 months after the diagnosis of the secondary tumor. Forty eight cases of NHL after treatment for HD have been previously reported. We present a review of the literature of these cases, adding to this literature the first reported case of gastric lymphoplasmacytoid lymphoma under such circumstances.
MeSH terms
-
Adolescent
-
Antineoplastic Combined Chemotherapy Protocols / adverse effects*
-
Cyclophosphamide / administration & dosage
-
Doxorubicin / administration & dosage
-
Head and Neck Neoplasms / drug therapy
-
Head and Neck Neoplasms / etiology*
-
Head and Neck Neoplasms / pathology
-
Hodgkin Disease / complications*
-
Hodgkin Disease / pathology
-
Hodgkin Disease / therapy
-
Humans
-
Leukemia, Lymphocytic, Chronic, B-Cell / drug therapy
-
Leukemia, Lymphocytic, Chronic, B-Cell / etiology*
-
Leukemia, Lymphocytic, Chronic, B-Cell / pathology
-
Lymphoma, Large-Cell, Immunoblastic / drug therapy
-
Lymphoma, Large-Cell, Immunoblastic / etiology*
-
Lymphoma, Large-Cell, Immunoblastic / pathology
-
Male
-
Middle Aged
-
Prednisone / administration & dosage
-
Radiotherapy / adverse effects*
-
Stomach Neoplasms / drug therapy
-
Stomach Neoplasms / etiology*
-
Stomach Neoplasms / pathology
-
Vincristine / administration & dosage
Substances
-
Vincristine
-
Doxorubicin
-
Cyclophosphamide
-
Prednisone