Background: Mucormycosis of the gastrointestinal tract is a rare fungal infection of neonates.
Case characteristics: 48-hours-old term neonate presented with intestinal obstruction and perforation. No significant risk factors were present. Histopathological examination of the resected gangrenous bowel revealed mucormycosis. Cutaneous involvement due to systemic spread led to dermal necrosis in toes.
Outcome: Though cutaneous lesions responded promptly to antifungal therapy, gastrointestinal manifestations required multiple antifungal therapy for prolonged period apart from surgical debridement.
Message: Precise histopathological diagnosis and early appropriate therapy can prevent dismal outcomes in neonatal mucormycosis.