Impact of a national nutritional support programme on loss to follow-up after tuberculosis diagnosis in Kenya

Int J Tuberc Lung Dis. 2018 Jun 1;22(6):649-654. doi: 10.5588/ijtld.17.0537.

Abstract

Setting: Undernourishment is prevalent among tuberculosis (TB) patients. Nutritional support is given to TB patients to prevent and treat undernourishment; it is also used to improve treatment outcomes and as an incentive to keep patients on treatment.

Objective: To determine whether nutritional support is associated with a reduction in the risk of loss to follow-up (LTFU) among TB patients in Kenya.

Design: This was a retrospective cohort study using national programmatic data. Records of 362 685 drug-susceptible TB patients from 2012 to 2015 were obtained from Treatment Information from Basic Unit (TIBU), a national case-based electronic data recording system. Patients who were LTFU were compared with those who completed treatment.

Results: Nutrition counselling was associated with an 8% reduction in the risk of LTFU (RR 0.92, 95%CI 0.89-0.95), vitamins were associated with a 7% reduction (adjusted RR [aRR] 0.93, 95%CI 0.90-0.96) and food support was associated with a 10% reduction (aRR 0.90, 95%CI 0.87-0.94). Among patients who received food support, the addition of nutrition counselling was associated with a 23% reduction in the risk of LTFU (aRR 0.77, 95%CI 0.67-0.88).

Conclusion: Nutritional support was associated with a reduction in the risk of LTFU. Providing nutrition counselling is important for patients receiving food support.

MeSH terms

  • Adolescent
  • Adult
  • Antitubercular Agents / therapeutic use*
  • Cohort Studies
  • Female
  • Follow-Up Studies
  • Humans
  • Kenya
  • Lost to Follow-Up
  • Male
  • Malnutrition / therapy*
  • Middle Aged
  • Nutritional Support / methods*
  • Patient Education as Topic / methods
  • Prevalence
  • Retrospective Studies
  • Risk Factors
  • Treatment Outcome
  • Tuberculosis / complications
  • Tuberculosis / diagnosis
  • Tuberculosis / therapy*
  • Young Adult

Substances

  • Antitubercular Agents