[Laryngopharyngeal reflux and chronic rhinosinusitis]

Chronic rhinosinusitis(CRS) is a highly prevalent disease, it affects approximately 2%-16% of the adult population. The prevalence of CRS is higher in patients with comorbid diseases, such as asthma, chronic obstructive pulmonary disease, and environmental allergies. The risk factors for chronic rhinosinusitis include genetic mutation, comorbid airway diseases and environmental factors.In recent years, some studies indicated that laryngopharyngeal reflux(LPR) was the potential risk factor for CRS. LPR is a kind of extraesophageal reflux.The diagnostic criteria for LPR include abnormal reflux symptom index, reflux findings score and ambulatory 24h double pHprobe monitoring. The pathogenic mechanisms involved in CRS related to LPR remains obscure. Some researches had shown that antireflux treatment could improve the syndrome of CRS patients. Further studies are need to explore the relationship between LPR and CRS.