Data on the experiments of temperature-sensitive hydrogels for pH-sensitive drug release and the characterizations of materials

Wei Zhang; Xin Jin; Heng Li; Run-Run Zhang; Cheng-Wei Wu

doi:10.1016/j.dib.2018.01.042

Data on the experiments of temperature-sensitive hydrogels for pH-sensitive drug release and the characterizations of materials

Data Brief. 2018 Jan 31:17:419-423. doi: 10.1016/j.dib.2018.01.042. eCollection 2018 Apr.

Authors

Wei Zhang¹, Xin Jin¹, Heng Li¹, Run-Run Zhang¹, Cheng-Wei Wu¹

Affiliation

¹ State Key Laboratory of Structure Analysis for Industrial Equipment, Department of Engineering Mechanics, Dalian University of Technology, Dalian 116024, China.

Abstract

This article contains experimental data on the strain sweep, the calibration curve of drug (doxorubicin, DOX) and the characterizations of materials. Data included are related to the research article "Injectable and body temperature sensitive hydrogels based on chitosan and hyaluronic acid for pH sensitive drug release" (Zhang et al., 2017) [1]. The strain sweep experiments were performed on a rotational rheometer. The calibration curves were obtained by analyzing the absorbance of DOX solutions on a UV-vis-NIR spectrometer. Molecular weight (M_w ) of the hyaluronic acid (HA) and chitosan (CS) were determined by gel permeation chromatography (GPC). The deacetylation degree of CS was measured by acid base titration.