Rapid progression to gummatous tertiary syphilis in a patient with HIV

Olivia A Charlton; Prianka Puri; Louella Davey; Chris Weatherall; Pamela Konecny

doi:10.1111/ajd.12860

Rapid progression to gummatous tertiary syphilis in a patient with HIV

Australas J Dermatol. 2019 Feb;60(1):e48-e50. doi: 10.1111/ajd.12860. Epub 2018 Jun 8.

Authors

Olivia A Charlton¹, Prianka Puri², Louella Davey³, Chris Weatherall^{4

5}, Pamela Konecny^{4

5}

Affiliations

¹ Department of Dermatology, Royal North Shore Hospital, Sydney, New South Wales, Australia.
² Department of Renal Medicine, Canberra Hospital, Canberra, Capital Territory, Australia.
³ Department of Anatomical Pathology, St George Hospital, Sydney, New South Wales, Australia.
⁴ Department of Infectious Diseases, Immunology and Sexual Health, St George Hospital, Sydney, New South Wales, Australia.
⁵ St George & Sutherland Clinical School, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia.

PMID: 29882582
DOI: 10.1111/ajd.12860

Abstract

Co-infection with human immunodeficiency virus-1 (HIV) and syphilis is associated with rapid progression to tertiary syphilis. This case report describes the early development of gummatous skin disease and suspected neurosyphilis in a patient with untreated HIV and approaches to treatment.

Keywords: HIV; gumma; syphilis; tertiary syphilis.

Publication types

Case Reports

MeSH terms

Adult
Coinfection / drug therapy
Disease Progression
HIV Infections / complications*
HIV Infections / drug therapy
HIV Infections / virology
HIV-1*
Humans
Male
Medication Adherence
Neurosyphilis / complications*
Neurosyphilis / drug therapy
Syphilis / complications*
Syphilis / drug therapy
Treatment Refusal

Supplementary concepts

Syphilis, tertiary