Abstract
Urokinase is one of the two plasminogen activators that catalyze the conversion of inactive plasminogen to plasmin. By combining somatic cell genetics, in situ hybridization, and Southern hybridization, we localized the human urokinase gene on the distal third of the long arm (q24-qter) of chromosome 10.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Chromosome Mapping
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Chromosomes, Human, 6-12 and X*
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DNA Restriction Enzymes / metabolism
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Humans
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Karyotyping
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Nucleic Acid Hybridization
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Urokinase-Type Plasminogen Activator / genetics*
Substances
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DNA Restriction Enzymes
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Urokinase-Type Plasminogen Activator