Massive Traumatic Skin Defect Successfully Treated with Autologous, Bilayered, Tissue-Engineered MyDerm Skin Substitute: A Case Report

JBJS Case Connect. 2018 Apr-Jun;8(2):e38. doi: 10.2106/JBJS.CC.17.00250.

Abstract

Case: A 22-year-old man sustained a laceration that measured 180 cm, after debridement, over the anterolateral aspect of the right leg following a road traffic accident. The wound was treated with MyDerm (Universiti Kebangsaan Malaysia), a cell-based, bilayered, bioengineered dermal substitute that contains no animal-derived components and is fully autologous. For its construction, only a small area of skin was harvested from the left groin, which was closed primarily with absorbable sutures.

Conclusion: MyDerm is an alternative option for the treatment of a massive skin defect in patients who desire removal of only a negligible amount of skin from the donor site and when use of an autograft is insufficient.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Humans
  • Lacerations / surgery*
  • Leg / pathology
  • Leg / surgery
  • Leg Injuries / surgery*
  • Male
  • Plastic Surgery Procedures / instrumentation*
  • Skin, Artificial*
  • Tissue Engineering
  • Transplantation, Autologous / instrumentation*
  • Young Adult