Is MDMX the better target?

Aging (Albany NY). 2018 Jun 13;10(6):1184-1185. doi: 10.18632/aging.101479.
No abstract available

Keywords: mdm2 KO; mdmx KO; p53 3KR mutant.

MeSH terms

  • Acetylation
  • Animals
  • Carcinogenesis
  • Gene Expression Regulation
  • Genes, Tumor Suppressor
  • Mice
  • Mice, Knockout
  • Mutation
  • Nuclear Proteins
  • Proto-Oncogene Proteins / genetics
  • Proto-Oncogene Proteins / metabolism*
  • Proto-Oncogene Proteins c-mdm2 / genetics
  • Proto-Oncogene Proteins c-mdm2 / metabolism*
  • Tumor Suppressor Protein p53 / genetics
  • Tumor Suppressor Protein p53 / metabolism*

Substances

  • FAM107A protein, human
  • Mdm4 protein, mouse
  • Nuclear Proteins
  • Proto-Oncogene Proteins
  • Tumor Suppressor Protein p53
  • Mdm2 protein, mouse
  • Proto-Oncogene Proteins c-mdm2