Peri-oral myoclonia with absences with multiple facial and upper body myoclonia: Overlap epilepsy syndrome

Pratima Gulati; Puneet Jain; Hebah Qashqari; Laura Bradbury; Pamela Cooper; Hiroshi Otsubo; Robyn Whitney

doi:10.1016/j.jocn.2018.06.008

Peri-oral myoclonia with absences with multiple facial and upper body myoclonia: Overlap epilepsy syndrome

J Clin Neurosci. 2018 Aug:54:135-137. doi: 10.1016/j.jocn.2018.06.008. Epub 2018 Jun 12.

Authors

Pratima Gulati¹, Puneet Jain², Hebah Qashqari³, Laura Bradbury⁴, Pamela Cooper⁵, Hiroshi Otsubo⁶, Robyn Whitney⁷

Affiliations

¹ Division of Neurology, The Hospital for Sick Children, Toronto, Ontario, Canada. Electronic address: [email protected].
² Division of Neurology, The Hospital for Sick Children, Toronto, Ontario, Canada. Electronic address: [email protected].
³ Division of Neurology, The Hospital for Sick Children, Toronto, Ontario, Canada. Electronic address: [email protected].
⁴ Division of Neurology, The Hospital for Sick Children, Toronto, Ontario, Canada. Electronic address: [email protected].
⁵ Community Pediatric Neurologist, Stouffville, Ontario, Canada. Electronic address: [email protected].
⁶ Division of Neurology, The Hospital for Sick Children, Toronto, Ontario, Canada. Electronic address: [email protected].
⁷ Division of Neurology, The Hospital for Sick Children, Toronto, Ontario, Canada. Electronic address: [email protected].

PMID: 29907391
DOI: 10.1016/j.jocn.2018.06.008

Abstract

A 17-years old girl presented with an 8-year history of absences with peri-oral twitching, eyelid twitching and head nodding, with poor response to anti-epileptic drugs. Video EEG revealed ictal and inter-ictal generalized spike wave discharges, and absences with peri-oral (predominant), eyelid, neck and shoulder myoclonia. There was also prominent eye closure sensitivity. Conundrums regarding epilepsy syndrome classification and pathophysiology are discussed.

Keywords: Absences; EEG; Eye closure sensitivity; Jeavons syndrome; POMA.

Publication types

Case Reports

MeSH terms

Adolescent
Electroencephalography
Epileptic Syndromes / diagnosis*
Epileptic Syndromes / physiopathology*
Female
Humans