Abstract
A bioinspired probe based on a zinc finger peptide functionalized by a lanthanide(iii)-DOTA monoamide complex turns out to be active for both luminescence and MRI detection of Zn2+, depending on the lanthanide cation. A mechanism for MRI-based detection is proposed.
MeSH terms
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Lanthanoid Series Elements / chemistry*
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Luminescence*
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Magnetic Resonance Imaging*
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Molecular Probes / chemistry*
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Organometallic Compounds / chemistry*
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Peptides / chemistry*
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Zinc / analysis*
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Zinc Fingers
Substances
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Lanthanoid Series Elements
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Molecular Probes
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Organometallic Compounds
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Peptides
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Zinc