A quantitative and semi-automatic measurement of transverse sinus stenosis improves idiopathic intracranial hypertension diagnostic accuracy

A Pellerin; J Aguilar Garcia; A David; J Meyer; B Guyomarch Delasalle; S De Gaalon; E Auffray Calvier; H Desal; R Bourcier

doi:10.1016/j.neurad.2018.05.001

A quantitative and semi-automatic measurement of transverse sinus stenosis improves idiopathic intracranial hypertension diagnostic accuracy

J Neuroradiol. 2018 Sep;45(5):329-332. doi: 10.1016/j.neurad.2018.05.001. Epub 2018 Jun 18.

Authors

A Pellerin¹, J Aguilar Garcia², A David², J Meyer³, B Guyomarch Delasalle⁴, S De Gaalon⁵, E Auffray Calvier², H Desal⁶, R Bourcier⁶

Affiliations

¹ Department of Neuroradiology, centre hospitalier universitaire de Nantes, hôpital Laënnec, boulevard Jacques-Monod Saint-Herblain, 44093 Nantes cedex 1, France. Electronic address: [email protected].
² Department of Neuroradiology, centre hospitalier universitaire de Nantes, hôpital Laënnec, boulevard Jacques-Monod Saint-Herblain, 44093 Nantes cedex 1, France.
³ Department of Radiology, centre hospitalier universitaire de Nantes, Hôtel-Dieu, 1, place Alexis-Ricordeau, 44093 Nantes cedex 1, France.
⁴ Inserm UMR 1087/CNRS UMR 6291, l'institut du Thorax, boulevard Jacques Monod Saint-Herblain, 44093 Nantes cedex 1, France.
⁵ Department of Neurology, centre hospitalier universitaire de Nantes, hôpital Laënnec, boulevard Jacques-Monod Saint-Herblain, 44093 Nantes cedex 1, France.
⁶ Department of Neuroradiology, centre hospitalier universitaire de Nantes, hôpital Laënnec, boulevard Jacques-Monod Saint-Herblain, 44093 Nantes cedex 1, France; Inserm UMR 1087/CNRS UMR 6291, l'institut du Thorax, IRS, Université de Nantes, 8, quai Moncousu, BP 70721, 44007 Nantes cedex 1, France.

PMID: 29913177
DOI: 10.1016/j.neurad.2018.05.001

Abstract

We propose a new reliable transverse sinus stenosis (TSS) index based on magnetic resonance venography (MRV) for the diagnosis of idiopathic intracranial hypertension (IIH). Our quantitative semi-automatic measurement analysis based on segmentation and cross-sectional TS diameter from 48 IIH patients and controls matched for age and sex, had a good inter-observer agreement (κ=0.729) compared to a visual examination (κ=0.467). A cut-off point≥2 discriminate IIH patients from controls, with a sensitivity and specificity of 100%.

Keywords: Idiopathic intracranial hypertension; Magnetic resonance venography; Transverse sinus; Venous stenosis.

MeSH terms

Adult
Case-Control Studies
Diagnosis, Differential
Female
Humans
Intracranial Hypertension / diagnostic imaging*
Magnetic Resonance Angiography / methods*
Male
Phlebography / methods*
Retrospective Studies
Sensitivity and Specificity
Transverse Sinuses / diagnostic imaging*
Transverse Sinuses / pathology