Lichen sclerosus in pregnancy: A review of 33 cases

Aust N Z J Obstet Gynaecol. 2018 Dec;58(6):686-689. doi: 10.1111/ajo.12812. Epub 2018 Jun 19.

Abstract

Vulval lichen sclerosus (VLS) is a chronic inflammatory skin condition affecting the anogenital area in women. Serious long-term consequences of VLS include the risk of developing squamous cell carcinoma of the vulva as well as of scarring and alteration of vulval architecture. The treatment of choice for genital lichen sclerosus in females is potent to very potent topical corticosteroids. There are few published data on the course of VLS in pregnancy. We present our experience of managing 33 pregnancies in 29 women with VLS.

Keywords: caesarean section; pregnancy; spontaneous vaginal delivery; topical corticosteroids; vulval lichen sclerosus.

MeSH terms

  • Administration, Topical
  • Adrenal Cortex Hormones / administration & dosage*
  • Cesarean Section
  • Delivery, Obstetric*
  • Female
  • Humans
  • Medication Adherence
  • Pregnancy
  • Pregnancy Complications / drug therapy*
  • Retrospective Studies
  • Severity of Illness Index
  • Vulvar Lichen Sclerosus / drug therapy*

Substances

  • Adrenal Cortex Hormones