Abstract
An EcoRI restriction fragment length polymorphism (RFLP) was detected in the 3' end of the locus of the c-erb-A proto-oncogene. The frequency of the rarer allele was around 3.0% in a normal population of 107 unrelated individuals. This frequency did not significantly differ in DNA samples from patients with breast tumors or acute leukemias.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alpharetrovirus / genetics*
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Avian Leukosis Virus / genetics*
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Breast Neoplasms / genetics
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Chromosome Mapping*
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Cloning, Molecular
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DNA Restriction Enzymes
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DNA, Neoplasm / genetics
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Deoxyribonuclease EcoRI
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Female
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Humans
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Leukemia / genetics
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Male
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Nucleic Acid Hybridization
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Oncogenes*
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Pedigree
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Polymorphism, Genetic*
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Proto-Oncogene Mas
Substances
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DNA, Neoplasm
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MAS1 protein, human
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Proto-Oncogene Mas
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DNA Restriction Enzymes
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Deoxyribonuclease EcoRI