U-BIOPRED: evaluation of the value of a public-private partnership to industry

Drug Discov Today. 2018 Sep;23(9):1622-1634. doi: 10.1016/j.drudis.2018.06.015. Epub 2018 Jun 21.

Abstract

Unbiased Biomarkers for the Prediction of Respiratory Disease Outcomes (U-BIOPRED) was initiated in the first year of the Innovative Medicines Initiative (IMI). It was an ambitious plan to tackle the understanding of asthma through an integration of clinical and multi-'omics approaches that necessitated the bringing together of industry, academic, and patient representatives because it was too large to be managed by any one of the partners in isolation. It was a novel experience for all concerned. In this review, we describe the main features of the U-BIOPRED experience from the industry perspective. We list some of the key advantages and learnings from the perspective of the authors, and also improvements that we feel could be made in future projects.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Anti-Asthmatic Agents / therapeutic use*
  • Asthma / diagnosis
  • Asthma / drug therapy*
  • Asthma / metabolism*
  • Asthma / physiopathology
  • Biomarkers / metabolism*
  • Consensus
  • Cooperative Behavior
  • Drug Discovery / methods*
  • Drug Discovery / organization & administration
  • Drug Industry / methods*
  • Drug Industry / organization & administration
  • Humans
  • Interdisciplinary Communication
  • Interinstitutional Relations
  • Phenotype
  • Program Development
  • Program Evaluation
  • Public-Private Sector Partnerships* / organization & administration
  • Stakeholder Participation
  • Workflow

Substances

  • Anti-Asthmatic Agents
  • Biomarkers