Renal Function Salvage After Delayed Endovascular Revascularization of Acute Renal Artery Occlusion in Patients With Fenestrated-Branched Endovascular Aneurysm Repair or Visceral Debranching

J Endovasc Ther. 2018 Aug;25(4):466-473. doi: 10.1177/1526602818783506. Epub 2018 Jun 29.

Abstract

Purpose: To analyze the renal function and outcome after delayed (>6 hours) endovascular revascularization of acute renal artery occlusion (RAO) in patients with fenestrated-branched endovascular aneurysm repairs (EVARs) or open visceral debranching.

Methods: A single-center retrospective analysis was conducted involving 7 patients (mean age 61 years, range 49-72; 5 women) with 9 RAOs treated with endovascular revascularization between December 2014 and March 2017. Three patients had a solitary kidney with chronic renal insufficiency; 1 patient had bilateral occlusions as the acute event. Initial aortic surgery included 5 branched and 1 fenestrated EVAR as well as 1 open visceral debranching operation. Revascularization of the RAO was performed using aspiration thrombectomy, local lysis therapy, and stent-graft relining. The median time between initial aortic surgery and RAO was 10 months (range 0.5-17).

Results: Median renal ischemic time to revascularization was 24 hours (range 7-168). Technical success was 100%, with 1 procedure-related access complication. Temporary dialysis dependency occurred in 4 patients. Mean in-hospital stay was 17 days (range 7-32) with 1 postoperative death at day 10 due to cardiac arrest of unknown cause. Mean follow-up was 10.3 months (range 1.5-27) in 5 of 6 discharged patients. During follow-up, 1 reintervention for recurrent occlusion was performed. At follow-up imaging, all renal arteries were patent. No permanent dialysis dependency occurred.

Conclusion: Renal function can be salvaged by delayed revascularization for RAO with prolonged renal ischemia. The endovascular approach with aspiration thrombectomy, local lysis, and stent-graft relining is a feasible technique for revascularization after RAO in patients with fenestrated-branched EVAR or open visceral debranching.

Keywords: acute kidney injury; aspiration thrombectomy; branched stent-graft; delayed revascularization; endovascular aneurysm repair; fenestrated stent-graft; renal artery occlusion; renal failure; renal function; visceral artery debranching.

MeSH terms

  • Acute Disease
  • Aged
  • Aneurysm / surgery*
  • Blood Vessel Prosthesis Implantation / adverse effects
  • Blood Vessel Prosthesis Implantation / instrumentation*
  • Blood Vessel Prosthesis*
  • Endovascular Procedures / adverse effects
  • Endovascular Procedures / instrumentation*
  • Female
  • Humans
  • Kidney / physiopathology*
  • Male
  • Middle Aged
  • Prosthesis Design
  • Recovery of Function
  • Renal Artery Obstruction / diagnostic imaging
  • Renal Artery Obstruction / etiology
  • Renal Artery Obstruction / physiopathology
  • Renal Artery Obstruction / surgery*
  • Retrospective Studies
  • Risk Factors
  • Stents*
  • Thrombectomy
  • Thrombolytic Therapy
  • Time Factors
  • Time-to-Treatment*
  • Treatment Outcome