Low urinary levels of angiotensin-converting enzyme 2 may contribute to albuminuria in children with sickle cell anaemia

Br J Haematol. 2019 Apr;185(1):190-193. doi: 10.1111/bjh.15439. Epub 2018 Jul 5.

Authors

André R Belisário^{1

2

3}, Érica L M Vieira², Jéssica A de Almeida², Fabíola G Mendes², Aline S Miranda², Paulo V Rezende³, Marcos B Viana³, Ana C Simões E Silva²

Affiliations

¹ Centro de Tecidos Biológicos de Minas Gerais, Fundação Hemominas, Lagoa Santa, MG, Brazil.
² Laboratório Interdisciplinar de Investigação Médica, Faculdade de Medicina, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil.
³ Faculdade de Medicina/Núcleo de Ações e Pesquisa em Apoio Diagnóstico (NUPAD), UFMG, Belo Horizonte, MG, Brazil.

PMID: 29974954
DOI: 10.1111/bjh.15439

No abstract available

Keywords: angiotensin-(1-7); angiotensin-converting enzyme 2; renin-angiotensin system; sickle cell anaemia; sickle cell nephropathy.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Age Factors
Albuminuria / diagnosis
Albuminuria / etiology*
Albuminuria / urine*
Anemia, Sickle Cell / complications*
Anemia, Sickle Cell / diagnosis
Angiotensin-Converting Enzyme 2
Biomarkers
Child
Disease Susceptibility
Humans
Peptidyl-Dipeptidase A / urine*
Renin-Angiotensin System

Substances

Biomarkers
Peptidyl-Dipeptidase A
ACE2 protein, human
Angiotensin-Converting Enzyme 2