Bone mineral content and bone density is lower in adolescents with type 1 diabetes: A brief report from the RESISTANT and EMERALD studies

Harsahiba Kaur; Prakriti Joshee; Stephanie Franquemont; Amy Baumgartner; Jessica Thurston; Laura Pyle; Kristen J Nadeau; Viral N Shah

doi:10.1016/j.jdiacomp.2018.06.004

Bone mineral content and bone density is lower in adolescents with type 1 diabetes: A brief report from the RESISTANT and EMERALD studies

J Diabetes Complications. 2018 Oct;32(10):931-933. doi: 10.1016/j.jdiacomp.2018.06.004. Epub 2018 Jun 15.

Authors

Harsahiba Kaur¹, Prakriti Joshee¹, Stephanie Franquemont², Amy Baumgartner³, Jessica Thurston⁴, Laura Pyle⁴, Kristen J Nadeau⁵, Viral N Shah⁶

Affiliations

¹ Barbara Davis Center for Diabetes, School of Medicine, University of Colorado Anschutz Medical Campus, 1775 Aurora Ct, Aurora, CO 80045, United States of America.
² Rocky Vista University College of Osteopathic Medicine, 8401 S Chambers Rd, Parker, CO 80134, United States of America.
³ University of Colorado School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, United States of America.
⁴ Department of Pediatrics, School of Medicine, Department of Biostatistics and Informatics, Colorado School of Public Health, 13001 E. 17th Place Mail Stop B119, Aurora, CO 80045, United States of America.
⁵ University of Colorado School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, United States of America; Division of Pediatric Endocrinology, Department of Pediatrics, Children's Hospital Colorado, Aurora, CO, United States of America.
⁶ Barbara Davis Center for Diabetes, School of Medicine, University of Colorado Anschutz Medical Campus, 1775 Aurora Ct, Aurora, CO 80045, United States of America; University of Colorado School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, United States of America. Electronic address: [email protected].

Abstract

To understand the effect of type 1 diabetes (T1D) on bone mineral content (BMC) and bone density (BMD), we studied 125 T1D adolescents and 80 pubertal stage matched controls. T1D was associated with lower whole-body BMC and BMD compared to controls, even when adjusted for age, sex and sex hormones.

Keywords: Adolescents; Bone health; Bone mineral content; Bone mineral density; Fracture risk; Type 1 diabetes.

MeSH terms

Adolescent
Bone Density*
Bone Diseases, Metabolic / epidemiology
Bone Diseases, Metabolic / etiology
Case-Control Studies
Child
Diabetes Mellitus, Type 1 / complications*
Diabetes Mellitus, Type 1 / epidemiology*
Diabetes Mellitus, Type 1 / physiopathology
Female
Fractures, Bone / epidemiology
Fractures, Bone / etiology
Humans
Male
Risk Factors
Young Adult

Abstract

MeSH terms

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