Objective: This study examined the effectiveness of an integrated programme in promoting physical activity, reducing fatigue, enhancing physical activity self-efficacy, muscle strength and quality of life among Chinese children with cancer.
Methods: A randomised controlled trial was conducted in a Hong Kong public hospital. Seventy eligible children were randomly assigned to an experimental group (n = 37) or a control group (n = 33). The experimental group received an integrated programme with 28 home visits from coaches over a 6-month period. The control group received a placebo intervention. The primary outcome was fatigue at 9 months (3 months after intervention completion). Secondary outcomes were physical activity levels, physical activity self-efficacy, muscle strength and quality of life at 9 months, assessed at baseline, and 6 and 9 months after starting the intervention.
Results: The experimental group reported significantly lower levels of cancer-related fatigue, higher levels of physical activity and physical activity self-efficacy, greater right- and left-hand grip strength and better quality of life than the control group at 9 months.
Conclusion: The programme is effective and feasible to implement among children with cancer and offers an alternative means of ameliorating the healthcare burden.
Practice implications: Healthcare professionals should build multidisciplinary partnerships to sustain such programmes.
Trial registration: ClinicalTrials.gov NCT02754973.
Keywords: Fatigue; Health promotion; Muscle strength; Paediatric patients with cancer; Physical activity; Physical activity self-efficacy; Quality of life.
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