Abstract
The complete genome sequences of both biotypes of a pair of bovine viral diarrhea viruses isolated from a bovid affected by mucosal disease were determined by next generation sequencing. The cytopathic virus possessed a 423-base insertion derived from bovine poly ubiquitin in the NS2/3 coding region and one nucleotide change. Both biotypes showed an additional glycosylation site in their N-terminus.
MeSH terms
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Animals
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Base Sequence
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Bovine Virus Diarrhea-Mucosal Disease / virology*
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Cattle
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Cytopathogenic Effect, Viral
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Diarrhea Viruses, Bovine Viral / classification
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Diarrhea Viruses, Bovine Viral / genetics*
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Diarrhea Viruses, Bovine Viral / isolation & purification
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Diarrhea Viruses, Bovine Viral / physiology
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Genome, Viral*
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High-Throughput Nucleotide Sequencing
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Phylogeny
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RNA, Viral / genetics