The ambitious role of anti angiogenesis molecules: Turning a cold tumor into a hot one

M Nuti; I G Zizzari; A Botticelli; A Rughetti; P Marchetti

doi:10.1016/j.ctrv.2018.07.016

The ambitious role of anti angiogenesis molecules: Turning a cold tumor into a hot one

Cancer Treat Rev. 2018 Nov:70:41-46. doi: 10.1016/j.ctrv.2018.07.016. Epub 2018 Jul 26.

Authors

M Nuti¹, I G Zizzari², A Botticelli³, A Rughetti², P Marchetti³

Affiliations

¹ Department of Experimental Medicine, University Sapienza, Rome, Italy. Electronic address: [email protected].
² Department of Experimental Medicine, University Sapienza, Rome, Italy.
³ Department of Clinical and Molecular Medicine, University Sapienza, Rome, Italy.

PMID: 30077081
DOI: 10.1016/j.ctrv.2018.07.016

Abstract

In renal cancer emerging treatment options are becoming available and there is a strong need to combine therapies to reformulate and adjourn clinical practice. We here highlight and discuss the need to take advantage of the common immune targets to design combined strategies to increase clinical responses.

Keywords: Angiogenesis; Immune system; Immunotherapy; Renal carcinoma; TKI.

Publication types

Review

MeSH terms

Angiogenesis Inhibitors / therapeutic use*
Humans
Immunotherapy*
Kidney Neoplasms / immunology*
Kidney Neoplasms / prevention & control*
Prognosis

Substances

Angiogenesis Inhibitors