1-Ethyl-7-[3-[(ethylamino)methyl]-1-pyrrolidinyl]-6,8-difluoro-1,4- dihydro-4-oxo-3-quinoline-carboxylic acid. New quinolone antibacterial with potent gram-positive activity

J Med Chem. 1986 Apr;29(4):445-8. doi: 10.1021/jm00154a003.
No abstract available

MeSH terms

  • Animals
  • Anti-Bacterial Agents / chemical synthesis
  • Anti-Bacterial Agents / pharmacology*
  • Gram-Positive Bacteria / drug effects*
  • Mice
  • Microbial Sensitivity Tests
  • Naphthyridines / chemical synthesis
  • Naphthyridines / pharmacology*
  • Quinolines / chemical synthesis
  • Quinolines / pharmacology*
  • Structure-Activity Relationship
  • Topoisomerase II Inhibitors

Substances

  • Anti-Bacterial Agents
  • Naphthyridines
  • Quinolines
  • Topoisomerase II Inhibitors