Pediatric extracorporeal cardiopulmonary resuscitation settled in an emergency department for a propafenone intentional intoxication

Am J Emerg Med. 2018 Nov;36(11):2132.e1-2132.e3. doi: 10.1016/j.ajem.2018.08.001. Epub 2018 Aug 3.

Abstract

The use of drugs in suicide attempts is becoming more and more frequent among adolescents. Intentional intoxication with propafenone is very rare and mainly reported in adults associated with other drugs. The therapeutic approach is symptomatic, since there is no specific antidote for propafenone. We present a pediatric case of intentional ingestion of 1.8 g of propafenone that caused refractory cardiogenic shock. The patient was successfully rescued with extracorporeal cardiopulmonary resuscitation in the emergency department of a secondary level peripheral hospital.

Keywords: Extracorporeal cardiopulmonary resuscitation; Intoxication; Pediatrics.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Anti-Arrhythmia Agents / poisoning*
  • Cardiopulmonary Resuscitation / methods
  • Electrocardiography
  • Emergency Service, Hospital
  • Female
  • Humans
  • Long QT Syndrome / chemically induced
  • Long QT Syndrome / physiopathology
  • Propafenone / poisoning*
  • Shock, Cardiogenic / chemically induced*
  • Shock, Cardiogenic / therapy
  • Suicide, Attempted*

Substances

  • Anti-Arrhythmia Agents
  • Propafenone