A case of pulmonary cryptococcoma due to Cryptococcus gattii in the United Kingdom

Isabel Rodriguez-Goncer; Felix Bongomin; Helen M Doran; Lily Novak-Frazer; Rikesh Masania; Caroline B Moore; Malcolm D Richardson

doi:10.1016/j.mmcr.2018.03.007

A case of pulmonary cryptococcoma due to Cryptococcus gattii in the United Kingdom

Med Mycol Case Rep. 2018 Mar 19:21:23-25. doi: 10.1016/j.mmcr.2018.03.007. eCollection 2018 Sep.

Authors

Isabel Rodriguez-Goncer¹, Felix Bongomin^{2

3}, Helen M Doran⁴, Lily Novak-Frazer^{2

5}, Rikesh Masania^{2

5}, Caroline B Moore^{2

5}, Malcolm D Richardson^{2

5}

Affiliations

¹ Department of Infectious Diseases, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester M23 9LT, UK.
² Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, UK.
³ Global Action Fund for Fungal Infections, Rue de l'Ancien-Port 14, 1211 Geneva 1, Switzerland.
⁴ Department of Pathology, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester M23 9LT, UK.
⁵ Mycology Reference Centre, ECMM Excellence Centre of Medical Mycology, Manchester University NHS Foundation Trust, Manchester M23 9LT, UK.

Abstract

We report a case of Cryptococcus gattii infection in the UK in a 76-year-old woman on biologic therapy for intra-abdominal non-Hodgkin lymphoma. An incidental nodular lung lesion was found on a chest imaging and histology, culture and molecular mycology studies of the lobectomy specimen revealed the presence of C. gattii.

Keywords: Biological therapy; Cryptococcus gattii; United Kingdom.