Cancer in People Living With HIV, Version 1.2018, NCCN Clinical Practice Guidelines in Oncology

J Natl Compr Canc Netw. 2018 Aug;16(8):986-1017. doi: 10.6004/jnccn.2018.0066.

Abstract

People living with HIV (PLWH) are diagnosed with cancer at an increased rate over the general population and generally have a higher mortality due to delayed diagnoses, advanced cancer stage, comorbidities, immunosuppression, and cancer treatment disparities. Lack of guidelines and provider education has led to substandard cancer care being offered to PLWH. To fill that gap, the NCCN Guidelines for Cancer in PLWH were developed; they provide treatment recommendations for PLWH who develop non-small cell lung cancer, anal cancer, Hodgkin lymphoma, and cervical cancer. In addition, the NCCN Guidelines outline advice regarding HIV management during cancer therapy; drug-drug interactions between antiretroviral treatments and cancer therapies; and workup, radiation therapy, surgical management, and supportive care in PLWH who have cancer.

Publication types

  • Practice Guideline

MeSH terms

  • Anti-HIV Agents / pharmacology
  • Anti-HIV Agents / therapeutic use
  • Antineoplastic Agents / pharmacology
  • Antineoplastic Agents / therapeutic use
  • Comorbidity
  • Drug Interactions
  • Evidence-Based Medicine / methods
  • Evidence-Based Medicine / standards
  • HIV / drug effects
  • HIV / isolation & purification
  • HIV Infections / drug therapy*
  • HIV Infections / epidemiology
  • HIV Infections / immunology
  • HIV Infections / virology
  • Healthcare Disparities / standards
  • Humans
  • Immunocompromised Host / drug effects
  • Immunocompromised Host / immunology
  • Immunocompromised Host / radiation effects
  • Medical Oncology / methods
  • Medical Oncology / standards*
  • Neoplasms / drug therapy*
  • Neoplasms / epidemiology
  • Neoplasms / immunology
  • Neoplasms / virology
  • Opportunistic Infections / immunology
  • Opportunistic Infections / prevention & control*
  • Opportunistic Infections / virology
  • Palliative Care / methods
  • Palliative Care / standards
  • Postoperative Complications / etiology
  • Postoperative Complications / prevention & control
  • Randomized Controlled Trials as Topic
  • Societies, Medical / standards
  • Surgical Procedures, Operative / adverse effects
  • Surgical Procedures, Operative / methods
  • Surgical Procedures, Operative / standards
  • United States

Substances

  • Anti-HIV Agents
  • Antineoplastic Agents