1 Division of Medicine, Akershus University Hospital, Lørenskog, Norway, and Center for Heart Failure Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Anestesia e Rianimazione, Azienda-Ospedaliero Universitaria S. Luigi Gonzaga, Orbassano, Italy, and Dipartimento di Oncologia, Università degli Studi di Torino, Turin, Italy; Department of Cardiovascular Research, IRCCS - Istituto di Ricerche Farmacologiche "Mario Negri", Milan, Italy; Department of Cardiovascular Research, IRCCS - Istituto di Ricerche Farmacologiche "Mario Negri," Milan, Italy; Division of Medicine, Akershus University Hospital, Lørenskog, Norway, and Center for Heart Failure Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.